Non disponible en dehors du Royaume-Uni et de l'Irlande
Biochem/physiol Actions
TP53 (tumor protein p53) gene is required for the DNA-damage checkpoint.This protein controls cell cycle, senescence and apoptosis upon oncogene activation, stress and DNA damage. Mutation in TP53 results in breast cancer.
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General description
TP53 (tumor protein p53) gene is located on human chromosome 17p13.1. This is a tumor-suppressor gene.
Immunogen
The antiserum was produced against synthesized peptide derived from human p53 around the phosphorylation site of Ser15.Immunogen Range: 1-50
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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