Non disponible en dehors du Royaume-Uni et de l'Irlande
Biochem/physiol Actions
PIK3R1 (phosphoinositide-3-kinase regulatory subunit 1) is known to mediate immune cell differentiation, development and function. Mutations in PIK3R1 gene result in SHORT syndrome, hyper IgM syndrome, lymphadenopathy and short stature.
Disclaimer
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Features and Benefits
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General description
PIK3R1 (phosphoinositide-3-kinase regulatory subunit 1) is a pleiotropic gene, that codes for a p85α regulatory subunit of phosphatidylinositol-3 kinase (PI3K). This gene is mapped to human chromosome 5q13.
Immunogen
The antiserum was produced against synthesized peptide derived from human PI3-kinase p85-alpha around the phosphorylation site of Tyr607.Immunogen Range: 573-622
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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