Non disponible en dehors du Royaume-Uni et de l'Irlande
Application
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.Western Blotting (1 paper)
Biochem/physiol Actions
Activated IRF3 (interferon regulatory factor 3) influences the expression of type I interferons via the toll-like receptor (TLR3/4)-mediated signaling pathway. IRF3 can suppress glioma invasion, proliferation and migration. Studies have suggested that IRF3 may have characteristics of tumor suppression.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Features and Benefits
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General description
IRF3 (interferon regulatory factor 3) is a transcription factor belonging to the IRF family and is involved in the innate immunity response against viruses and bacteria. The gene encoding IRF3 is localized on human chromosome 19q13.33.
Immunogen
The antiserum was produced against synthesized peptide derived from human IRF-3 around the phosphorylation site of Ser396.Immunogen Range: 362-411
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :