Anti-CEP135, anticorps C - Terminal produit en lapin, environ 1 mg / mL, anticorps isolé affinité, solution aqueuse tamponnée

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

Anti-CEP135, C-Terminal antibody has been used in immunofluorescence staining.

Biochem/physiol Actions

Mutation in Cep135 (centrosomal protein 135) result in primary microcephaly. It induces centriole assembly and stability. CEP135 helps to maintain the structure and organization of microtubules. This protein plays a major role in centriole biogenesis.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

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General description

Cep135 (centrosomal protein 135) is a cartwheel protein. It has a coiled-coil domain and conserved regions near the N-terminus and the C-terminus, respectively. It is mapped to human chromosome 4q12.

Anti-CEP135 Antibody detects endogenous levels of total CEP135 protein.

Immunogen

The antiserum was produced against synthesized peptide derived from human CEP135.Immunogen Range: 1081-1130

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.