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Biochem/physiol Actions
Mutation in G protein-coupled receptor 101 (GPR101) gene result in acromegaly. The GPR101 protein is expected to play an important role in hypothalamic control of energy homeostasis. Duplication of the GPR101 gene leads to X-linked acrogigantism (XLAG).
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General description
G protein-coupled receptor 101 (GPR101) codes for an an orphan G protein-coupled receptor. It is expressed at high level in the hypothalamus. The GPR101 gene is mapped to human chromosome Xq26.3.
Anti-GPR101 Antibody detects endogenous levels of total GPR101 protein.
Immunogen
The antiserum was produced against synthesized peptide derived from human GPR101.Immunogen Range: 451-500
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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