Anticorps Anti - CAMK2 produit en lapin, environ 1 mg/ mL, anticorps isolé affinité, solution aqueuse tamponnée

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

Calmodulin dependent protein kinase II complex δ (CAMK2D) modulates the functions of ion channels and Ca²⁺ handling proteins. It also regulates the phosphorylation and acetylation of histones. It has been shown to be overexpressed in the myocardium of diabetic patients.

Calcium/calmodulin dependent protein kinase II α (CAMK2) is essential for long-term potentiation (LTP) and spatial memory. It regulates synaptic plasticity. Dysfunctionin this gene is associated with schizophrenia, epilepsy and autism spectrum disorders.

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Features and Benefits

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General description

Anti-CAMK2 Antibody detects endogenous levels of total CAMK2 protein.

Calcium/calmodulin dependent protein kinase II α (CAMK2) is a calcium-activated serine/threonine kinase. The gene is located on human chromosome 5q32. CAMK2 is mainly expressed in the central nervous system. It consists of a kinase domain, a regulatory domain and an association domain.

Immunogen

The antiserum was produced against synthesized peptide derived from human CaMK2 alpha/delta.Immunogen Range: 256-305

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.