Anti-TNFA antibody produced in rabbit, approx. 1 mg/mL, affinity isolated antibody, buffered aqueous solution

Not available outside of the UK & Ireland.

Biochem/physiol Actions

The TNFA (tumor necrosis factor α) gene is significantly associated with the regulation of innate and adaptive immune responses. Polymorphism of TNFA gene is known to cause acute motor axonal neuropathy. The cytokine release and gene action is associated with epithelial cells, myeloid cells, endothelial, as well as tumor cells. Tumor cells are known to release TNFA, specifically in response to chemotherapy

Disclaimer

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Features and Benefits

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General description

Anti-TNFA Antibody detects endogenous levels of total TNFA protein.

The TNFA (tumor necrosis factor α) gene is mapped to human chromosome 6p21.33 and codes for a pro-inflammatory cytokine.

Immunogen

The antiserum was produced against synthesized peptide derived from human TNFA.Immunogen Range: 141-190

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.