Non disponible en dehors du Royaume-Uni et de l'Irlande
Biochem/physiol Actions
Synuclein β reduces the effects of synuclein α toxicity in a dose dependent manner by preventing its accumulation. Synuclein β normally, does not form fibrils.
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Features and Benefits
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General description
Anti-Synuclein β antibody detects endogenous levels of total Synuclein β protein.
The SNCB (synuclein β) gene is mapped to the chromosome 5q35.2. Synuclein β is known to localize along with synuclein α in the presynaptic region of the brain. It contains KTKXGV repeats at its N-terminal, highly acidic and solubilizing region at its C-terminal and a non-amyloid-β component.
Immunogen
The antiserum was produced against synthesized peptide derived from human Synuclein beta.Immunogen Range: 85-134
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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