Non disponible en dehors du Royaume-Uni et de l'Irlande
Biochem/physiol Actions
The SMO (smoothened) gene encodes a protein that mediates hedgehog signaling for embryonic development and to maintain tissue homeostasis. SMO participates in tumor cell proliferation.
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General description
Anti-SMO antibody detects endogenous levels of total SMO protein.
The SMO (smoothened) gene is mapped to human chromosome 7q32.1. It encodes a protein that belongs to the frizzled family of G protein-coupled receptors. It is a seven transmembrane protein and highly conserved.
Immunogen
The antiserum was produced against synthesized peptide derived from human SMO.Immunogen Range: 68-117
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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