Anti-Aggrecan (Cleaved -Asp369), anticorps N-Terminal produit en lapin, environ 1 mg / mL, anticorps isolé affinité, solution aqueuse tamponnée

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

Anti-Aggrecan (Cleaved-Asp369), N-Terminal antibody has been used in western blotting and immunostaining.

Biochem/physiol Actions

Mutations in aggrecan results in autosomal dominant short stature with accelerated skeletal maturation. Mutation in the variable repeat region of the aggrecan gene (AGC1) leads to spondyloepiphyseal dysplasia.

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Features and Benefits

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General description

Aggrecan is a large aggregating chondroitin sulfate proteoglycan of the human cartilage. It is encoded by AGC1 (aggrecan) gene. It is located on human chromosome 15q26.1.

Anti-Aggrecan (Cleaved-Asp³⁶⁹) Antibody detects endogenous levels of fragment of activated Aggrecan (Cleaved-Asp³⁶⁹) protein.

Immunogen

The antiserum was produced against synthesized peptide derived from human Aggrecan.Immunogen Range: 320-369

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.