Anticorps Anti - caténine - bêta produit en lapin, environ 1 mg / mL, anticorps isolé affinité,solution aqueuse tamponnée

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

Mutations in β-Catenin results in retinal vascular condition FEVR (familial exudative vitreoretinopathy). It participates in stimulating disease progression, providing to BCR–ABL (fusion gene) kinase-independent resistance and LSC (leukemic stem cell) self-renewal. It plays an important role in cell-to-cell adhesion and transcriptional modulation in the Wnt signalling pathway.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

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General description

Anti-Catenin-β Antibody detects endogenous levels of total Catenin-β protein.

Catenin-β is a multifunctional protein, coded by CTNNB1 (catenin β 1) gene. It is present in the intracellular side of the cytoplasmic membrane. It is located on human chromosome 3p22.1.

Immunogen

The antiserum was produced against synthesized peptide derived from human Catenin-beta.Immunogen Range: 455-504

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.