Anti-Claudin 7, anticorps C - Terminal produit en lapin, environ 1 mg / mL, anticorps isolé affinité, solution aqueuse tamponnée

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

In HCC827 and NCI-H358 lung cancer cells, suppression of claudin-7 decreases the expression of integrin β1. Claudins are important constituents of tight junctions (TJ) in the upper region of epithelial cells.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

General description

Claudin 7 is a tight junction membrane protein that belongs to claudins (cld) family. It is upregulated at high level in the upper gastrointestinal tract and the liver. It is located on human chromosome 17p13.

Anti-Claudin 7 Antibody detects endogenous levels of total Claudin 7 protein.

Immunogen

The antiserum was produced against synthesized peptide derived from human Claudin 7.Immunogen Range: 162-211

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.