Anti-COX41, anticorps N-Terminal produit en lapin, environ 1 mg/ mL, anticorps isolé affinité, solution aqueuse tamponnée

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

COX4 isoform 1 (COX4-1) (COX4-1) may play an important role in glioma chemoresistance. It regulates the upregulation of BMI1 (polycomb complex protein BMI1). It is necessary for the multiplication of GBM (glioblastoma multiforme). In cells, expression of COX4-1 is necessary to maintain the stability of mitochondria and ROS (reactive oxygen species) homeostasis.

Disclaimer

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Features and Benefits

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General description

Anti-COX41 Antibody detects endogenous levels of total COX41 protein.

COX41 (cytochrome c oxidase subunit 4I1) is located on human chromosome 16q24. COX4NB (COX4 neighbour) and COX4I1 (COX4 isoform 1) belongs to the cytochrome C oxidase subunit IV (COX4) family.

Immunogen

The antiserum was produced against synthesized peptide derived from human COX41.Immunogen Range: 11-60

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.