Anti-TSH2, anticorps C - Terminal produit en lapin, environ 1 mg/ mL, anticorps isolé affinité, solution aqueuse tamponnée

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

TSH2/TSHZ2 (teashirt zinc finger homeobox 2) acts as a C-terminal binding protein (CtBP)-dependent transcriptional repressor. At the time of mammary tumorigenesis, low level expression of TSH2 liberates GLI1 (glioma-associated oncogene homolog 1) from the nuclear repressor complex to update its transcriptional activity.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

General description

Anti-TSH2 Antibody detects endogenous levels of total TSH2 protein.

TSH2/TSHZ2 (teashirt zinc finger homeobox 2) is a nuclear protein. It has four zinc-finger (ZF) domains, a homeobox domain and a coiled-coil domain. It is located on human chromosome 20q13.2.

Immunogen

The antiserum was produced against synthesized peptide derived from human TSH2.Immunogen Range: 811-860

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.