Protéine Anti - centromérique un anticorps produit en lapin, environ 1 mg / mL, anticorps isolé affinité, solution aqueuse tamponnée

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

Centromeric Protein A (CENPA) plays a vital role in centromere specification and facilitates its mitotic function and epigenetic maintenance. CENP-A-nucleosome associated complex (NAC) is implicated in the regulation of chromosome congression and spindle bipolarity. Disorganization of this complex leads to change in chromosome alignment and segregation that prevent cell survival regardless of continued centromere-derived mitotic checkpoint signaling.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

General description

Centromeric Protein A (CENPA), is encoded by the gene mapped to human chromosome 2p23.3. The encoded protein is a longer variant of histone H3 in humans.

Anti-Centromeric protein A Antibody detects endogenous levels of total Centromeric protein A protein.

Immunogen

The antiserum was produced against synthesized peptide derived from human Centromeric Protein A.Immunogen Range: 1-50

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.