Non disponible en dehors du Royaume-Uni et de l'Irlande
Biochem/physiol Actions
G3BP1 (ras-GTPase-activating protein SH3 domain-binding protein 1) blocks the replication of HIV-1 (human immunodeficiency virus) in macrophages and T-cells. In gastric cancer patients, overexpression of G3BP1 leads to imperfect clinical predictions. It is required for the interactions of SG–PB (stress granule-processing bodies).
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General description
Anti-G3BP-1 Antibody detects endogenous levels of total G3BP-1 protein.
G3BP1 (ras-GTPase-activating protein SH3 domain-binding protein 1) is a constituent of SGs (stress granules). It is located on human chromosome 5q14.2-5q33.3.
Immunogen
The antiserum was produced against synthesized peptide derived from human G3BP-1.Immunogen Range: 199-248
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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