Anticorps Anti - phospho - Ephrin - B2 (pTyr316) produit dans un anticorps isolé rabbit affinity

Non disponible en dehors du Royaume-Uni et de l'Irlande

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General description

The antibody detects endogenous levels of Ephrin-B2 only when phosphorylated at tyrosine 316.

Immunogen

Peptide sequence around phosphorylation site of tyrosine 316 (P-V-Yp-I-V), according to the protein NP_004084.1

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Target description

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5′ UTR but that encode the same protein have been identified for this gene.