Anticorps Anti - SMAD1 (Ab - 465) produit dans un anticorps isolé rabbit affinity

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

SMAD1 (SMAD family member 1) protein has a major role in disease development, hence it acts as a biologic prognostic factor in diseases. The miR-345 repress the multiplication, invasion and migration of prostate cancer by downregulating Smad1.

Disclaimer

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Features and Benefits

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General description

Smad1 (SMAD family member 1) is a transcriptional activator, that is located on chromosome 4q31.

Immunogen

Peptide sequence around aa. 461-465 (I-S-S-V-S), according to the protein SMAD1.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Target description

Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD).