Non disponible en dehors du Royaume-Uni et de l'Irlande
Biochem/physiol Actions
NK2 homeobox 1(NKX2-1) has a role in the development of thyroid glands, lungs and brain. It modulates gene expression during embryogenesis. NKX2-1 has been found to be expressed in adenocarcinoma and small cell lung cancer. This protein acts as an immunohistological marker to distinguish between primary lung carcinoma and non-pulmonary cancer.
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General description
NK2 homeobox 1 (NKX2-1) is expressed in epithelial cells of the thyroid gland and lungs. The gene encoding NKX2-1 is localized on human chromosome 14q13.
Immunogen
Antibody was raised against a 16 amino acid peptide near the amino terminus of human NKX2-1.
Linkage
The action of this antibody can be blocked using blocking peptide SBP3500757.
Physical form
Supplied at 1 mg/mL in PBS with 0.02% sodium azide.
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