Anticorps Anti - AFP produit dans le lapin, anticorps isolé affinité, solution aqueuse tamponnée

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

Anti-AFP antibody produced in rabbit has been used in immunoflorescence.

Biochem/physiol Actions

α-fetoprotein encoded by the gene AFP is involved in the regulation of fatty acids in both fetal and proliferating adult liver cells. Its expression is found to be increased in acute liver injuries, indicating active liver regeneration. It has been associated with fatty liver disease (FLD), a disease that may lead to cirrhosis and hepatocellular carcinoma. It serves as a tumor marker for HCC (hepatocellular carcinoma).

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

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General description

The gene AFP (α fetoprotein) encodes a plasma glycoprotein that has a molar mass of 70kDa. The gene is mapped to human chromosome 4. The gene is evolutionarily-related to serum albumin, which is also mapped to human chromosome 4. It is synthesized along with serum albumin during the development of embryonic yolk sac and the liver.

Immunogen

AFP antibody was raised against a 14 amino acid peptide near the amino terminus of human AFP.

Linkage

The action of this antibody can be blocked using blocking peptide SBP3500533.

Physical form

Supplied in PBS with 0.02% sodium azide.