Non disponible en dehors du Royaume-Uni et de l'Irlande
Application
Anti-PTK7 antibody has been used in immunohistochemistry.
Biochem/physiol Actions
Protein tyrosine kinase-7 (PTK7) stimulates cell proliferation and invasion. It plays a vital role embryonic development and disease. PTK7 controls radioresistance with the help of nuclear factor-κ B in esophageal squamous cell carcinoma.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Features and Benefits
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General description
Protein tyrosine kinase-7 (PTK7) is a transmembrane receptor, that belongs to the receptor protein tyrosine kinase (RTKs) family. It has an extracellular immunoglobulin-like domain, a transmembrane domain and an inert tyrosine kinase-like domain. PTK7 is located on human chromosome 6p21.
Immunogen
PTK7 antibody was raised against a 18 amino acid peptide from near the carboxy terminus of human PTK7.
Linkage
The action of this antibody can be blocked using blocking peptide SBP3500340.
Physical form
Supplied in PBS with 0.02% sodium azide.
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