Anticorps Anti - DDAH2 produit en chèvre, anticorps isolé affinity, solution aqueuse tamponnée

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

Anti-DDAH2 antibody produced in goat is suitable for indirect ELISA and western blot applications.

Biochem/physiol Actions

DDAH2 (Dimethylarginine dimethylaminohydrolase 2) Activity partly determines the cellular concentration of methylarginine. Concentration of ADMA (asymmetrical dimethylarginine) in endothelial cells is increased on the advent of pharmacological inhibition of DDAH, which also leads to the inhibition of NO-mediated endothelium dependent relaxation of blood vessels.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

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General description

DDAH (Dimethylarginine dimethylaminohydrolase) exists as two isoforms; DDAH1, and DDAH2. Tissues expressing endothelial nitric oxide synthases is predominated by DDAH2.

Immunogen

Peptide with sequence SSLCLVLSTRPHS from the C Terminus of the protein sequence according to NP_039268.1.

Physical form

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.