Non disponible en dehors du Royaume-Uni et de l'Irlande
Biochem/physiol Actions
Choline acetyltransferase (CHAT) is involved in the synthesis of acetylcholine in neurons. It catalyzes the transfer of an acetyl group between acetyl-coenzyme A and choline. Mutations in the gene encoding this protein have been associated with congenital neuromuscular disorders.
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General description
Choline acetyltransferase (CHAT) has a molecular weight of about 68kDa. It is synthesized in the parakaryon and is transported to the axon terminals. CHAT is part of the choline/carnitine acyltransferase family.
Immunogen
Peptide with sequence CKEKATRPSQGHQP from the C Terminus of the protein sequence according to NP_065574; NP_066264; NP_066265; NP_066266.
Physical form
Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.
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