ANTI-TLR6 antibody produced in mouse, clone 4F4, purified immunoglobulin, buffered aqueous solution

Not available outside of the UK & Ireland.

General description

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor functionally interacts with toll-like receptor 2 to mediate cellular response to bacterial lipoproteins. (provided by RefSeq)

Immunogen

TLR6 (NP_006059, 301 a.a. ~ 430 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.Sequencekttlkaltie hitnqvflfs qtalytvfse mnimmltisd tpfihmlcph apstfkflnf tqnvftdsif ekcstlvkle tlilqknglk dlfkvglmtk dmpsleildv swnslesgrh kenctwvesi

Physical form

Solution in phosphate buffered saline, pH 7.4