Non disponible en dehors du Royaume-Uni et de l'Irlande
Biochem/physiol Actions
Pyrroline-5-carboxylate reductase 1 (PYCR1) acts as a prognostic biomarker for breast cancer.Mutations in this gene affects mitochondrial function and is associated with connective tissue disorder cutis laxa.It helps in cell metabolism.This protein catalyses the conversion of 1-piperideine-6-carboxylate (P6C) into pipecolic acid.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
Pyrroline-5-carboxylate reductase 1 (PYCR1) is a housekeeping gene.The gene is located on human chromosome 17q25.3.
Immunogen
PYCR1 (NP_008838.2, 1 a.a. ~ 319 a.a) full-length human protein.SequenceMSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSALRKMGVKLTPHNKETVQHSDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLSAFRPAPRVIRCMTNTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCTEVEEDLIDAVTGLSGSGPAYAFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATIHALHVLESGGFRSLLINAVEASCIRTRELQSMADQEQVSPAAIKKTILDKVKLDSPAGTALSPSGHTKLLPRSLAPAGKD
Physical form
Solution in phosphate buffered saline, pH 7.4
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