Anticorps Monoclonal Anti - MAP3K15 produit dans la souris, clone 1H7, immunoglobulin purifiée, solution aqueuse tamponnée

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

Mitogen-activated protein kinase kinase kinase 15 (MAP3K15) modulates blood pressure in the kidney. It has a role in signal transduction cascades related to apoptotic cell death initiated due to cellular stress. ASK3 has been shown to protect HeLa cells against cytotoxicity induced by oxidative stress, antibodies or proteins.

General description

Mitogen-activated protein kinase kinase kinase 15 (MAP3K15) belongs to the group of apoptosis signal-regulating kinases. It is expressed in the kidney and the gene encoding it is localized on human chromosome Xp22.12.

Immunogen

MAP3K15 (NP_001001671, 691 a.a. ~ 786 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.SequenceLYHLQLKLKSNCITENPAGPYGQRTDKELIDWLRLQGADAKTIEKIVEEGYTLSDILNEITKEDLRYLRLRGGLLCRLWSAVSQYRRAQEASETKD

Physical form

Solution in phosphate buffered saline, pH 7.4