Monoclonal Anti-NPHS1 antibody produced in mouse, clone 3H6, purified immunoglobulin, buffered aqueous solution

Not available outside of the UK & Ireland.

General description

Nephrin is a kidney glomerular filtration barrier protein that is an essential component of the interpodocyte-spanning slit diaphragm. Mutations in the nephrin gene are associated with congenital nephrotic syndrome (NPHS1; MIM 256300).[supplied by OMIM

Immunogen

NPHS1 (NP_004637.1, 33 a.a. ~ 122 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.SequenceGFWALPENLTVVEGASVELRCGVSTPGSAVQWAKDGLLLGPDPRIPGFPRYRLEGDPARGEFHLHIEACDLSDDAEYECQVGRSEMGPEL

Physical form

Solution in phosphate buffered saline, pH 7.4