Anti-EDA (center) antibody produced in rabbit, saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution

Not available outside of the UK & Ireland.

General description

EDA is a type II membrane protein that can be cleaved by furin to produce a secreted form. This protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in the gene for EDA are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia.

Immunogen

EDA (NP_001390, 143-177)This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human EDA.

Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.