Anticorps Anti - KLF4 produit dans le lapin, sulfate d'ammonium saturé (SAS) précipité, solution aqueuse TAMPONNÉE

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

Krüppel-like factor 4 (KLF4) is involved in cell growth, proliferation and differentiation in the colon. It is down-regulated in both mouse and human colonic adenomas. The protein has been implicated as a tumor suppressor in the gut, whereas in breast cancer, KLF4 is an oncogene. It is also involved in reprogramming differentiated cells into pluripotent stem cells.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Krüppel-like factor 4 (KLF4) is a transcription factor. It can act both as a transcriptional activator or repressor. The gene encoding this protein is localized on human chromosome 9q31.2.

Immunogen

KLF4 (NP_004226.3, )This antibody is generated from rabbits immunized with a his tag recombinant protein of human KLF4.

Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.