Anticorps Anti - BCCIP (C - term) produit dans le lapin, sulfate d'ammonium saturé (SAS) précipité, solution aqueuse TAMPONNÉE

Non disponible en dehors du Royaume-Uni et de l'Irlande

General description

BCCIP was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21.

Immunogen

BCCIP (NP_510869, 263-302)This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human BCCIP.

Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.