Non disponible en dehors du Royaume-Uni et de l'Irlande
General description
TRPCs, mammalian homologs of the Drosophila transient receptor potential (trp) protein, are ion channels that are thought to mediate capacitative calcium entry into the cell. TRP-PLIK is a protein that is both an ion channel and a kinase. As a channel, it conducts calcium and monovalent cations to depolarize cells and increase intracellular calcium. As a kinase, it is capable of phosphorylating itself and other substrates. The kinase activity is necessary for channel function, as shown by its dependence on intracellular ATP and by the kinase mutants.[supplied by OMIM]
Immunogen
CHAK1 (Q9BXB2, 1825-1859)This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human CHAK1.
Physical form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :