ANTI-ARL1 (N-TERM)

Not available outside of the UK & Ireland.

General description

ARL1 belongs to the ARL (ADP-ribosylation factor-like) family of proteins, which are structurally related to ADP-ribosylation factors (ARFs). ARFs, described as activators of cholera toxin (CT) ADP-ribosyltransferase activity, regulate intracellular vesicular membrane trafficking, and stimulate a phospholipase D (PLD) isoform. Although, ARL proteins were initially thought not to activate CT or PLD, later work showed that they are weak stimulators of PLD and CT in a phospholipid dependent manner.

Immunogen

ARL1 (NP_001168, 3-32)This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human ARL1.

Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.