Anticorps Anti - PYGM (C -term)produit en lapin, fraction Ig d' antisérum, solution aqueuse tamponnée

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

PYGM catalyses and regulates the breakdown of glycogen to glucose-1-phosphate. Defects in PYGM are the cause of Glycogenosis type V/ glycogen storage disease type 5 (GSD5), also known as McArdle disease/ myophosphorylase deficiency, is an autosomal recessive disorder. GSD5 is a metabolic disorder resulting in myopathy characterized by exercise intolerance, cramps, muscle weakness and recurrent myoglobinuria.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Glycogen phosphorylase, muscle associated (PYGM) encodes glycogen phosphorylase or myophosphorylase. In human chromosome, the gene PYGM is localized on 11q13.1.

Immunogen

PYGM (NP_005600, 703-737)This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human PYGM.

Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.