Anti-Hspb3 (11-25)

Not available outside of the UK & Ireland.

Application

Anti-HSPB3 (11-25) antibody produced in rabbit has been used in western blotting and immunoelectron microscopy.

Biochem/physiol Actions

Heat shock protein family B (small) member 3 (HSPB3) has molecular chaperone-like activity in inhibiting the heat-induced aggregation of alcohol dehydrogenase (ADH). HSPB is critical for the development and maintenance of muscles. Mutations in HSPB3 are associated with distal hereditary motor neuropathy type 2C (dHMN2C).

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Heat shock protein family B (small) member 3 (HSPB3) is a member of HSPB family. It is expressed in skeletal and cardiac muscles. HSPB3 gene is located on human chromosome location 5q11.2.

Immunogen

synthetic peptide corresponding to amino acids 11-25of human HSPB3

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.