Anticorps Anti - SDCBP produit en lapin, environ 1,0 mg/ mL, anticorps isolé affinité, solution aqueuse tamponnée

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

Anti-SDCBP antibody produced in rabbit has been used in: enzyme linked immuno sorbent assay (ELISA) immunoblotting immunocytochemistry

Biochem/physiol Actions

Syndecan binding protein (SDCBP) regulates cytoskeletal-membrane organization, cell adhesion, protein trafficking and the activation of transcription factors. SDCBP promotes metastasis in human melanoma cells by activating c-Src.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Syndecan binding protein (SDCBP), also known as syntenin and melanoma differentiation associated gene-9 (mda-9), was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. SDCBP contains tandemly repeated PDZ domains that binds the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. SDCBP is primarily localized to membrane associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus.

Physical form

Solution in 0.01 M phos­phate buffered saline, pH 7.4, containing 15 mM sodium azide.