Anticorps Anti - Nhe - 1(ab2 )produit dans le lapin, anticorps isolé affinité, solution aqueuse tamponnée

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

Anti-Nhe-1 (ab2) antibody has been used in immunohistochemistry.

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.Immunohistochemistry (1 paper)

Biochem/physiol Actions

Na⁺/H⁺ exchanger 1 (NHE1) modulates intracellular pH by exchanging a proton for an extracellular sodium ion and affects cell growth, proliferation, migration and apoptosis. It plays a major role in cancers including breast cancer, hepatocellular carcinoma, colon cancer, pancreatic ductal adenocarcinoma, prostate cancer, cervical cancer and neuroblastoma.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

SLC9A1 (solute carrier family 9 member A1)/Na⁺/H⁺ exchanger 1 (NHE1), a plasma membrane transporter, is mapped to human chromosome 1p36. It belongs to the NHE family. NHE1 is abundantly expressed in all organisms.

Immunogen

a 17 amino acid peptide near the center of the human Nhe-1.

Linkage

The action of this antibody can be blocked using blocking peptide SBP4379.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide