Anti-Hyaluronan synthase 2; clone 2B11.1

Non disponible en dehors du Royaume-Uni et de l'Irlande

Analysis Note

ControlMRC-5 cell lysate

Application

Research CategoryApoptosis & Cancer

Detect Hyaluronan synthase 2 using this mouse monoclonal antibody, Anti-Hyaluronan synthase 2 Antibody, clone 2B11.1 validated for use in western blotting & IHC (Paraffin).

Research Sub CategoryApoptosis - Additional

Western Blotting Analysis: 2.0 µg/mL from a representative lot detected Hyaluronan synthase 2 in 10 µg of K562 cell lysate.
Immunohistochemistry Analysis: A 1:250 dilution from a representative lot detected Hyaluronan synthase 2 in human breast adenocarcinoma cell tissue.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Hyaluronan synthase 2 (HAS2) is also known as Hyaluronate synthase 2, or Hyaluronic acid (HA) synthase 2. As the name suggests, HAS2 is involved in hyaluronan/hyaluronic acid synthesis. Hyaluronan synthase 2 is expressed in fibroblasts. Chromosomal aberrations involving Hyaluronan synthase 2 may be a cause of lipoblastomas, usually diagnosed in children.

Immunogen

Epitope: Cytoplasmic domain

GST-tagged recombinant protein corresponding to the cytoplasmic domain of human Hyaluronan synthase 2.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Protein G Purified

Format: Purified

Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Quality

Evaluated by Western Blotting in MRC-5 cell lysate.

Western Blotting Analysis: 0.2 µg/mL of this antibody detected Hyaluronan synthase 2 in 200 µg of MRC-5 cell lysate.

Specificity

This antibody recognizes the cytoplasmic domain of Hyaluronan synthase 2.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Target description

~ 64 kDa observed