Non disponible en dehors du Royaume-Uni et de l'Irlande
Application
IgM, λ from murine myeloma was used as standard in ELISA and as isotype control in immunohistochemistry applications.
Biochem/physiol Actions
IgM antibodies are produced initially during B-cell development. IgM participates in opsonization and compliment fixation. Defect in IgM production is observed in X-linked agammaglobulinemia.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
IgM antibodies are present as pentamers in the serum and are produced in response to antigens IgM, λ from murine myeloma is produced by MOPC 104E tumor line introduced subcutaneously in BALB/c mice. It specifically recognizes mouse IgM, λ. Identity and purity of the immunoglobulin is established by immunoelectrophoresis.
Physical form
Solution in 0.05 M Tris, 0.5 M sodium chloride, pH 8.0, containing 0.02% sodium azide
Specificity
Antigen Specificity: α(1→3) glucose
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