Anti-gsk3b

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

Anti-GSK3β antibody produced in chicken is suitable for indirect ELISA and western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Biochem/physiol Actions

Glycogen synthase kinase 3β is an enzyme encoded by the GSK3B gene in humans. It is closely related to protein-serine kinases and acts as an inhibitory component of Wnt signalling during embryonic development, and cell proliferation in adult tissues. GSK-3β helps in facilitating NF-κB function. It is a key endogenous factor for specifically regulating oligodendrogenesis. The genotypes may interact with major depressive disorder (MDD). GSK-3β is a proline-directed kinase that helps in forming part of the wingless signaling pathway.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

Synthetic peptide sequence of glycogen synthase kinase 3β.

Immunogen Sequence: GI # 21361340, sequence 21-36

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide.