Anti-Human Ig; Fab2;Gt; .5MG

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

This Goat anti-Human IgM+IgG+IgA Antibody, F(ab′)2 is validated for use in ELISA for the detection of Human IgM+IgG+IgA.

Research Sub CategoryFragment Specific Secondary Antibodies

Research CategorySecondary & Control Antibodies

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

IgG is the most abundant immunoglobulin comprising two heavy chains and two light chains. Each molecule has two antigen binding sites. IgG has 4 subclasses: IgG1 (66%), IgG2 (23%), IgG3 (7%) and IgG4 (4%). IgM constitutes about 10% of serum immunoglobulins. IgM (with IgD) is the major immunoglobulin expressed on the surface of B cells. Monomeric IgA constitutes 5-15 % of the serum immunoglobulins whereas dimeric IgA is localized to mucosa surfaces.

Immunogen

Epitope: Human IgM, IgG, IgA

Prepared from pepsin digest of human Ig.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Physical form

Gel filtration chromatography

Purified by gel filtration chromatography of pepsin digested antibody. Liquid in 1.0 mL of 100 mM borate buffered saline, pH 8.2.

Specificity

The antibody reacts with the heavy and light chains of human IgM, IgG and IgA, and with the light chains of human IgD as demonstrated by ELISA and flow cytometry.

Reacts with the heavy and light chains of human IgM, IgG and IgA, and with the light chains of human IgD.

Storage and Stability

Maintain refrigerated at 2°-8°C under sterile conditions for up to twelve months from date of receipt.