Non disponible en dehors du Royaume-Uni et de l'Irlande
Analysis Note
ControlHuman neural stem cells, Raji cell lysate.
Application
Western Blot:
1:200-1:1,000 dilution using ECL.
Immunohistochemistry:
1:200-1:1,000 dilution of a previous lot worked.
Optimal working dilutions must be determined by the end user.
Research CategoryNeuroscience
Research Sub CategoryDevelopmental NeuroscienceNeuronal & Glial Markers
This Anti-HES-1 Antibody is validated for use in IH, WB for the detection of HES-1.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
Hes1 is a transcriptional repressor of genes that require a bHLH protein for their transcription. It may act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Hes1 is expressed in developing neuroectodermal and endodermal endocrine tissues, and Hes1 deficient embryos show severe defects in neuronal development, as well as pancreatic hypoplasia.
Immunogen
Synthetic peptide.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Physical form
ImmunoAffinity Purified
Purified rabbit polyclonal in buffer containing a solution of 50% saturated ammonium sulfate and PBS containing no preservatives.
Specificity
Reactivity with other species has not been confirmed.
Recognizes HES-1 (Hairy family), a Helix-loop-helix class of transcription factor.
Storage and Stability
Stable for 1 year at -80°C from date of receipt.
Target description
29 kDa
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :