Non disponible en dehors du Royaume-Uni et de l'Irlande
Application
Peroxynitrite has been used to induce pericyte contraction in mouse brains. It has also been used for the preparation of positive control nitrated protein standards in immunohistochemical studies.
Biochem/physiol Actions
Peroxynitrite (ONOO−) exhibits bactericidal activity. It promotes cell death and contributes to the signal-transduction process, mitochondrial function, and apoptotic pathway. The formation of peroxynitrite has been associated with the development of various diseases including vascular diseases, ischemia-reperfusion injury, circulatory shock, inflammation, pain, and neurodegeneration.
General description
Peroxynitrite (ONOO−) is a powerful oxidant formed by the collision of nitric oxide and superoxide.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Physical form
0.3M NaOH
Quality
Routinely evaluated by treating non-stimulated A431 cells.
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :