PACAP 38, ⅛ 1 pc x 0,1 MG

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

Cell permeable: no

Reversible: no

Primary TargetAdenylate cyclase

Product does not compete with ATP.

EC50 = 7 nM against adenylate cyclase

General description

More active than vasoactive intestinal peptide (VIP) in stimulating adenylate cyclase (EC₅₀ = 7 nM).

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Kobayashi, H., et al. 1994. Brain Res.647, 145.Chastre, E., et al. 1991. J. Biol. Chem.266, 21239.Le Meuth, V., et al. 1991. Am. J. Physiol. 260, G265.Kimura, C., et al. 1990. Biochem. Biophys. Res. Commun.166, 81.

Packaging

Yes

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Sequence

H-His-Ser-Asp-Gly-Ile-Phe-Thr-Asp-Ser-Tyr-Ser-Arg-Tyr-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Ala-Ala-Val-Leu-Gly-Lys-Arg-Tyr-Lys-Gln-Arg-Val-Lys-Asn-Lys-NH₂

Warning

Toxicity: Standard Handling (A)