Hydrochlorure TP - 238

Name: Hydrochlorure TP - 238
Brand: SIGMA-ALDRICH
SKU: SML2434-25MG
Price: 582.90 USD

Code: SML2434-25MG D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

TP-238 is a chemical probe for CECR2 (cat eye syndrome chromosome region, candidate 2), a gene expressed in the nervous system involved in neurulation...

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Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

TP-238 is a chemical probe for CECR2 (cat eye syndrome chromosome region, candidate 2), a gene expressed in the nervous system involved in neurulation, and for BPTF bromodomains. It has an activity of 10-30 nM with CECR2 and 100-350 nM with BPTF. TP-238 showed an IC₅₀ of 30nM against CECR2 and 350nM against BPTF in an alphascreen assay and a KD of 10nM for CECR2 and 120nM for BPTF by ITC. The structurally related negative control TP-422 is completely inactive against BPTF and CECR2.

assay	≥98% (HPLC)
color	white to beige
form	powder
Quality Level	100
solubility	DMSO: 2 mg/mL, clear
storage temp.	−20°C

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Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :

Hydrochlorure TP - 238

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