Non disponible en dehors du Royaume-Uni et de l'Irlande
Application
1S,3R-RSL 3 has been used:as a glutathione peroxidase 4 (GPX4) inhibitor to study its effects on cell death in subventricular glioblastoma multiforme (GBM) linesGPX4 inhibitor and ferroptosis inducer to study its effects on cardiomyocyte death and heart failure in miceas a ferroptosis inducer in HT-1080 cellsin cell viability assay
Biochem/physiol Actions
RSL3 is an inducer of ferroptosis. It acts by a different method than erastin to induce ferroptosis by inhibiting glutathione peroxidase 4 (GPX4).
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :