Staurosporine solution de Streptomyces sp., Solution prête à l'emploi, 1 mM en DMSO (100 mug/ 214 muL), avec filtre 0,2 mum

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

Staurosporine solution from Streptomyces sp. was used to study the effect of PKC inhibition on signaling mediated by angiotensin II.³ It was used to induce cell death in Jurkat cells.⁴

Biochem/physiol Actions

Potent inhibitor of phospholipid/calcium-dependent protein kinase. Inhibits the upregulation of VEGF expression in tumor cells.

Potent cell-permeable inhibitor of protein kinase C. Induces apoptosis in Jurkat cells.

General description

Chemical structure: indol derivative

Packaging

200 µL in glass bottle