Not available outside of the UK & Ireland.
Application
2-(Diphenylphosphanyl)benzamide (DPBM) is a phosphine useful in the Staudinger reduction in chemical biology and medicinal chemistry. Recently, DPBM was demonstrated to faciliate the reactivation of CRISPR/Cas9 functions by removing azidomethylnicotinyl (AMN) groups used to masked gRNA and inhibit CRISPR systems. AMN groups were originally added with the use of RNA probe NAI-N3 (cat# 913812).
General description
It is recommended to make fresh stock stolutions prior to each use.
Other Notes
Conditional control of RNA-guided nucleic acid cleavage and gene editingSmall-molecule control of protein function through Staudinger reductionA FRET-based ratiometric two-photon fluorescent probe for dual-channel imaging of nitroxyl in living cells and tissues
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