Non disponible en dehors du Royaume-Uni et de l'Irlande
Biochem/physiol Actions
Reversible: no
Target IC50: 200 µM against adenylate cyclase
Product does not compete with ATP.
Primary Targetadenylate cyclase
Cell permeable: yes
General description
Cell-permeable adenylate cyclase inhibitor. Blocks PTH-stimulation of adenylate cyclase (IC50 = 200 µM). Reduces PGE2-induced inhibition of O2⋅– production.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Other Notes
Talpain, E., et al. 1995. Br. J. Pharmacol. 114, 1459.Tamaoki, J., et al. 1993. Prostaglandins45, 363.Fabbri, E., et al. 1991. J. Enzyme Inhib.5, 87.Goldsmith, B.A. and Abrams, T.W. 1991. Proc. Natl. Acad. Sci. USA 88, 9021.
Packaging
5 mg in Glass bottle
Reconstitution
Following reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 2 weeks at 4°C.
Warning
Toxicity: Irritant (B)
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :