Non disponible en dehors du Royaume-Uni et de l'Irlande
Biochem/physiol Actions
Reversible: no
Product does not compete with ATP.
Primary TargetInduction of nitric oxide synthase activity in rat alveolar macrophages
Cell permeable: yes
General description
Cell permeable. Inhibits the induction of nitric oxide synthase activity in rat alveolar macrophages. Prevents apoptosis in human HL-60 cells and thymocytes, but induces apoptosis in human and rat smooth muscle cells. Inhibits NF-κB activation and HIV replication in lymphocytes.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Other Notes
Tsai, J.C., et al. 1996. J. Biol. Chem.271, 3667.Pan, Z., et al. 1995. J. Biol. Chem.270, 7787.Bessho, R., et al. 1994. Biochem. Pharmacol.48, 1883.Sherman, M.P., et al. 1993. Biochem. Biophys. Res. Commun.191, 1301.Schreck, R., et al. 1992. J. Exp. Med.175, 1181.
Packaging
100 mg in Plastic ampoule
Reconstitution
Following reconstitution, aliquot and freeze (-20°C). Aqueous stock solutions are stable for up to 3 months at -20°C.r>r>r>r>From Catalog:r>Desc. Field- added "cell-permeable"
Warning
Toxicity: Irritant (B)
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :