8-Methoxymethyl-3-isobutyl-1-methylxanthine

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

Target IC₅₀: 4 µM against Ca2+-calmodulin-dependent phosphodiesterase (PDE I)

Reversible: no

Product does not compete with ATP.

Cell permeable: yes

Primary TargetPDE 1

General description

A cell-permeable selective inhibitor of Ca²⁺-calmodulin-dependent phosphodiesterase (PDE I; IC₅₀ = 4 µM).

A cell-permeable, selective inhibitor of Ca²⁺-calmodulin-dependent phosphodiesterase (PDE I, IC₅₀ = 4 µM).

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Jackson, E.K., et al. 1997. J. Cardiovasc. Pharmacol. 30, 798.Ahn, H.S., et al. 1989. Biochem. Pharmacol.38, 3331.Han, P., et al. 1989. J. Biol. Chem.274, 22337.

Packaging

10 mg in Plastic ampoule

Reconstitution

Following reconstitution aliquot and freeze at -20°C. Stock solutions are stable for up to 3 months at -20°C.

Warning

Toxicity: Standard Handling (A)